Inhibitory Activity of 4-O-Benzoyl-3′-O-(OMethylsinapoyl) Sucrose from Polygala tenuifolia on Escherichia coli β-Glucuronidase

Bacterial β-glucuronidase in the intestine is involved in the conversion of 7-ethyl-10- hydroxycamptochecin glucuronide (derived from irinotecan) to 7-ethyl-10-hydroxycamptothecin, which causes intestinal bleeding and diarrhea (side effects of anti-cancer drugs). Twelve compounds (1–12) from Polygal...

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Detalles Bibliográficos
Autores principales: Kim, Jang Hoon, Vinh, Le Ba, Hur, Mok, Koo, Sung-Cheol, Park, Woo Tae, Moon, Youn-Ho, Lee, Yoon Jeong, Kim, Young Ho, Huh, Yun-Chan, Yang, Seo Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Microbiology and Biotechnology 2021
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705844/
https://www.ncbi.nlm.nih.gov/pubmed/34528918
http://dx.doi.org/10.4014/jmb.2108.08004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705844/
https://www.ncbi.nlm.nih.gov/pubmed/34528918
http://dx.doi.org/10.4014/jmb.2108.08004

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