Picropodophyllotoxin Induces G1 Cell Cycle Arrest and Apoptosis in Human Colorectal Cancer Cells via ROS Generation and Activation of p38 MAPK Signaling Pathway

Picropodophyllotoxin (PPT), an epimer of podophyllotoxin, is derived from the roots of Podophyllum hexandrum and exerts various biological effects, including anti-proliferation activity. However, the effect of PPT on colorectal cancer cells and the associated cellular mechanisms have not been studie...

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Detalles Bibliográficos
Autores principales: Lee, Seung-On, Kwak, Ah-Won, Lee, Mee-Hyun, Seo, Ji-Hye, Cho, Seung-Sik, Yoon, Goo, Chae, Jung-Il, Joo, Sang Hoon, Shim, Jung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Microbiology and Biotechnology 2021
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705953/
https://www.ncbi.nlm.nih.gov/pubmed/34528917
http://dx.doi.org/10.4014/jmb.2109.09012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705953/
https://www.ncbi.nlm.nih.gov/pubmed/34528917
http://dx.doi.org/10.4014/jmb.2109.09012

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