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SRSF1 acts as an IFN-I-regulated cellular dependency factor decisively affecting HIV-1 post-integration steps

Efficient HIV-1 replication depends on balanced levels of host cell components including cellular splicing factors as the family of serine/arginine-rich splicing factors (SRSF, 1–10). Type I interferons (IFN-I) play a crucial role in the innate immunity against HIV-1 by inducing the expression of IF...

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Detalles Bibliográficos
Autores principales: Sertznig, Helene, Roesmann, Fabian, Wilhelm, Alexander, Heininger, Delia, Bleekmann, Barbara, Elsner, Carina, Santiago, Mario, Schuhenn, Jonas, Karakoese, Zehra, Benatzy, Yvonne, Snodgrass, Ryan, Esser, Stefan, Sutter, Kathrin, Dittmer, Ulf, Widera, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706209/
https://www.ncbi.nlm.nih.gov/pubmed/36458014
http://dx.doi.org/10.3389/fimmu.2022.935800