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Prediction of total and renal clearance of renally secreted drugs in neonates and infants (≤3 months of age)
BACKGROUND: Renal excretion is a major route of elimination for many drugs. Renal clearance is the sum of three processes: glomerular filtration, tubular secretion, and tubular re-absorption. Tubular secretion is an active transport process and is immature at birth. In the neonates, renal tubular se...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Whioce Publishing Pte. Ltd.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706311/ https://www.ncbi.nlm.nih.gov/pubmed/36452002 |