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Genetic encoding of isobutyryl-, isovaleryl-, and β-hydroxybutryl-lysine in E. coli

Here we report the synthesis and genetic encoding of the lysine post translational modifications, β-hydroxybutyryl-lysine, isobutyryl-lysine and isovaleryl-lysine. The ability to obtain a homogenous protein samples with site-specific incorporation of these acylated lysine residues can serve as a pow...

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Detalles Bibliográficos
Autores principales: Christopher, Jayani A., Galbada Liyanage, Sahan A., Nicholson, Eve M., Kinney, William D., Cropp, T. Ashton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706372/
https://www.ncbi.nlm.nih.gov/pubmed/36545614
http://dx.doi.org/10.1039/d2ra04898a