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TOPAS, a network-based approach to detect disease modules in a top-down fashion

A vast scenario of potential disease mechanisms and remedies is yet to be discovered. The field of Network Medicine has grown thanks to the massive amount of high-throughput data and the emerging evidence that disease-related proteins form ‘disease modules’. Relying on prior disease knowledge, netwo...

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Detalles Bibliográficos
Autores principales: Buzzao, Davide, Castresana-Aguirre, Miguel, Guala, Dimitri, Sonnhammer, Erik L L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706483/
https://www.ncbi.nlm.nih.gov/pubmed/36458021
http://dx.doi.org/10.1093/nargab/lqac093