Cargando…
TOPAS, a network-based approach to detect disease modules in a top-down fashion
A vast scenario of potential disease mechanisms and remedies is yet to be discovered. The field of Network Medicine has grown thanks to the massive amount of high-throughput data and the emerging evidence that disease-related proteins form ‘disease modules’. Relying on prior disease knowledge, netwo...
Autores principales: | Buzzao, Davide, Castresana-Aguirre, Miguel, Guala, Dimitri, Sonnhammer, Erik L L |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706483/ https://www.ncbi.nlm.nih.gov/pubmed/36458021 http://dx.doi.org/10.1093/nargab/lqac093 |
Ejemplares similares
-
Benefits and Challenges of Pre-clustered Network-Based Pathway Analysis
por: Castresana-Aguirre, Miguel, et al.
Publicado: (2022) -
Drug repurposing improves disease targeting 11-fold and can be augmented by network module targeting, applied to COVID-19
por: Rivero-García, Inés, et al.
Publicado: (2021) -
Pathway-specific model estimation for improved pathway annotation by network crosstalk
por: Castresana-Aguirre, Miguel, et al.
Publicado: (2020) -
PathwAX II: network-based pathway analysis with interactive visualization of network crosstalk
por: Ogris, Christoph, et al.
Publicado: (2022) -
Network Crosstalk as a Basis for Drug Repurposing
por: Guala, Dimitri, et al.
Publicado: (2022)