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Single nuclei RNA sequencing investigation of the Purkinje cell and glial changes in the cerebellum of transgenic Spinocerebellar ataxia type 1 mice

Glial cells constitute half the population of the human brain and are essential for normal brain function. Most, if not all, brain diseases are characterized by reactive gliosis, a process by which glial cells respond and contribute to neuronal pathology. Spinocerebellar ataxia type 1 (SCA1) is a pr...

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Detalles Bibliográficos
Autores principales: Borgenheimer, Ella, Hamel, Katherine, Sheeler, Carrie, Moncada, Francisco Labrada, Sbrocco, Kaelin, Zhang, Ying, Cvetanovic, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706545/
https://www.ncbi.nlm.nih.gov/pubmed/36457352
http://dx.doi.org/10.3389/fncel.2022.998408