Cargando…
Single nuclei RNA sequencing investigation of the Purkinje cell and glial changes in the cerebellum of transgenic Spinocerebellar ataxia type 1 mice
Glial cells constitute half the population of the human brain and are essential for normal brain function. Most, if not all, brain diseases are characterized by reactive gliosis, a process by which glial cells respond and contribute to neuronal pathology. Spinocerebellar ataxia type 1 (SCA1) is a pr...
Autores principales: | Borgenheimer, Ella, Hamel, Katherine, Sheeler, Carrie, Moncada, Francisco Labrada, Sbrocco, Kaelin, Zhang, Ying, Cvetanovic, Marija |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706545/ https://www.ncbi.nlm.nih.gov/pubmed/36457352 http://dx.doi.org/10.3389/fncel.2022.998408 |
Ejemplares similares
-
Spatial and Temporal Diversity of Astrocyte Phenotypes in Spinocerebellar Ataxia Type 1 Mice
por: Rosa, Juao-Guilherme, et al.
Publicado: (2022) -
BDNF is altered in a brain-region specific manner and rescues deficits in Spinocerebellar Ataxia Type 1
por: Rosa, Juao-Guilherme, et al.
Publicado: (2023) -
Brain Derived Neurotrophic Factor (BDNF) Delays Onset of Pathogenesis in Transgenic Mouse Model of Spinocerebellar Ataxia Type 1 (SCA1)
por: Mellesmoen, Aaron, et al.
Publicado: (2019) -
Extracellular Matrix Regulation in Physiology and in Brain Disease
por: Soles, Alyssa, et al.
Publicado: (2023) -
Altered calcium signaling in Bergmann glia contributes to spinocerebellar ataxia type-1 in a mouse model of SCA1
por: Nanclares, Carmen, et al.
Publicado: (2023)