Mutant Kras and mTOR crosstalk drives hepatocellular carcinoma development via PEG3/STAT3/BEX2 signaling

Background & Aims: Abnormal activation of mTOR through loss of tuberous sclerosis complex (Tsc) frequently occurs in hepatocellular carcinoma (HCC). Mutant Kras could induce aggressive HCCs. Here, we aim to identify the predictive or prognostic biomarkers for HCC patients with Kras mutant and mT...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Yuan-Deng, Liu, Xiao-Yu, Fang, Lei, Yu, Hong-Qiang, Zhang, Yu-Jun, Chen, Min, Zhang, Lei-Da, Xie, Chuan-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706580/
https://www.ncbi.nlm.nih.gov/pubmed/36451866
http://dx.doi.org/10.7150/thno.76873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706580/
https://www.ncbi.nlm.nih.gov/pubmed/36451866
http://dx.doi.org/10.7150/thno.76873

Ejemplares similares