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The difficulty in translating the preclinical success of combined TGFβ and immune checkpoint inhibition to clinical trial
Immune checkpoint inhibitors (ICIs) have transformed the treatment paradigm for solid tumors. However, even in cancers generally considered ICI-sensitive, responses can vary significantly. Thus, there is an ever-increasing interest in identifying novel means of improving therapeutic responses, both...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706619/ https://www.ncbi.nlm.nih.gov/pubmed/36455409 http://dx.doi.org/10.1016/j.ebiom.2022.104380 |