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Plasma complement C3 and C3a are increased in major depressive disorder independent of childhood trauma

BACKGROUND: Dysregulated complement system is linked to pathophysiology of major depressive disorder (MDD). Childhood trauma has been associated with an increased incidence of adult depression via a putative mechanism of immune activation. This study aimed to measure and compare peripheral levels of...

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Detalles Bibliográficos
Autores principales: Luo, Xianmei, Fang, Zeman, Lin, Lingyun, Xu, Haiyun, Huang, Qingjun, Zhang, Handi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706857/
https://www.ncbi.nlm.nih.gov/pubmed/36447174
http://dx.doi.org/10.1186/s12888-022-04410-3