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Nasal irrigation with licorice extract (Glycyrrhiza glabra) in treating nasal polyps by reducing fibroblast differentiation and extracellular matrix production in TGF-β1-stimulated nasal polyp-derived fibroblasts by inhibiting the MAPK/ERK-1/2 pathway – an in vitro and in clinic study

BACKGROUND: To date, treating nasal polyps (NPs) is still a medical challenge. However, we have developed an innovative therapy using licorice extract (LE: Glycyrrhiza glabra) to treat rhinitis and sinusitis via nasal irrigation and have discovered that it significantly affects treatment of NPs. HYP...

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Detalles Bibliográficos
Autores principales: Chang, Geng-He, Yang, Pei-Rung, Cheng, Yu-Ching, Hsu, Ke-Hsin, Wu, Ching-Yuan, Yang, Yao-Hsu, Lin, Yu-Shih, Hsu, Cheng-Ming, Tsai, Ming-Shao, Tsai, Yao-Te, Chang, Pey-Jium
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706886/
https://www.ncbi.nlm.nih.gov/pubmed/36447209
http://dx.doi.org/10.1186/s12906-022-03791-y