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Cefazolin and imipenem enhance AmpC expression and resistance in NagZ-dependent manner in Enterobacter cloacae complex

BACKGROUND: Enterobacter cloacae complex (ECC) is a common opportunistic pathogen and is responsible for causing various infections in humans. Owing to its inducible chromosomal AmpC β-lactamase (AmpC), ECC is inherently resistant to the 1st- and 2nd- generation cephalosporins. However, whether β-la...

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Detalles Bibliográficos
Autores principales: Yang, Xianggui, Wang, Zhenguo, Liu, Mingquan, Yu, Xuejing, Zhong, Yuanxiu, Wang, Fuying, Xu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706910/
https://www.ncbi.nlm.nih.gov/pubmed/36443681
http://dx.doi.org/10.1186/s12866-022-02707-7