Aryloxypropanolamine targets amyloid aggregates and reverses Alzheimer-like phenotypes in Alzheimer mouse models

BACKGROUND: Aggregated amyloid-β (Aβ) is considered a pathogenic initiator of Alzheimer’s disease (AD), in strong association with tau hyperphosphorylation, neuroinflammation, synaptic dysfunction, and cognitive decline. As the removal of amyloid burden from AD patient brains by antibodies has shown...

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Detalles Bibliográficos
Autores principales: Lee, Hee Yang, Yoon, Soljee, Lee, Jeong Hwa, Park, Keunwan, Jung, Youngeun, Cho, Illhwan, Lee, Donghee, Shin, Jisu, Kim, Kyeonghwan, Kim, Sunmi, Kim, Jimin, Kim, Koeun, Han, Seung Hoon, Kim, Seong Muk, Kim, Hye Ju, Kim, Hye Yun, Kim, Ikyon, Kim, Young Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706920/
https://www.ncbi.nlm.nih.gov/pubmed/36443837
http://dx.doi.org/10.1186/s13195-022-01112-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706920/
https://www.ncbi.nlm.nih.gov/pubmed/36443837
http://dx.doi.org/10.1186/s13195-022-01112-6

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