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The conversion of β-carotene to vitamin A in adipocytes drives the anti-obesogenic effects of β-carotene in mice

OBJECTIVE: The β-carotene oxygenase 1 (BCO1) is the enzyme responsible for the cleavage of β-carotene to retinal, the first intermediate in vitamin A formation. Preclinical studies suggest that BCO1 expression is required for dietary β-carotene to affect lipid metabolism. The goal of this study was...

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Detalles Bibliográficos
Autores principales: Coronel, Johana, Yu, Jianshi, Pilli, Nageswara, Kane, Maureen A., Amengual, Jaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707038/
https://www.ncbi.nlm.nih.gov/pubmed/36400405
http://dx.doi.org/10.1016/j.molmet.2022.101640