Methotrexate-induced acute cardiotoxicity requiring veno-arterial extracorporeal membrane oxygenation support: a case report

BACKGROUND: Methotrexate is an antifolate antimetabolite that inhibits the activity of dihydrofolate reductase by acting as a false substrate, which leads to defects of DNA synthesis, specifically the inhibition of purine and pyrimidine synthesis. Thus, methotrexate is a powerful agent for treating...

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Detalles Bibliográficos
Autores principales: Shah, Sareena, Haeger-Overstreet, Kristen, Flynn, Brigid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707053/
https://www.ncbi.nlm.nih.gov/pubmed/36443884
http://dx.doi.org/10.1186/s13256-022-03644-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707053/
https://www.ncbi.nlm.nih.gov/pubmed/36443884
http://dx.doi.org/10.1186/s13256-022-03644-9

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