RF22 | PSUN318 Hepatocytes Exposed to PFOA Prior to Differentiation Leads to Epigenetic Changes in Genes Linked With NAFLD

BACKGROUND: Perfluorooctanoic acid (PFOA), is a persistent fluorinated compound with oil and water repelling properties found in cookware, food packaging and municipal water systems. Adult animals exposed to PFOA develop hepatomegaly, fatty liver, peroxisome proliferation, and immunotoxicity. Rodent...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Weixuan, Joshi, Apoorva, Pinney, Sara Elizabeth, Tarapore, Pheruza, Wang, Zhiping, Green, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Endocrine Disruption
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707057/
http://dx.doi.org/10.1210/jendso/bvac150.933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707057/
http://dx.doi.org/10.1210/jendso/bvac150.933

Ejemplares similares