A terminal functionalization strategy reveals unusual binding abilities of anti-thrombin anticoagulant aptamers

Despite their unquestionable properties, oligonucleotide aptamers display some drawbacks that continue to hinder their applications. Several strategies have been undertaken to overcome these weaknesses, using thrombin binding aptamers as proof-of-concept. In particular, the functionalization of a th...

Descripción completa

Detalles Bibliográficos
Autores principales: Troisi, Romualdo, Riccardi, Claudia, Pérez de Carvasal, Kévan, Smietana, Michael, Morvan, François, Del Vecchio, Pompea, Montesarchio, Daniela, Sica, Filomena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707062/
https://www.ncbi.nlm.nih.gov/pubmed/36457701
http://dx.doi.org/10.1016/j.omtn.2022.11.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707062/
https://www.ncbi.nlm.nih.gov/pubmed/36457701
http://dx.doi.org/10.1016/j.omtn.2022.11.007

Ejemplares similares