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A terminal functionalization strategy reveals unusual binding abilities of anti-thrombin anticoagulant aptamers
Despite their unquestionable properties, oligonucleotide aptamers display some drawbacks that continue to hinder their applications. Several strategies have been undertaken to overcome these weaknesses, using thrombin binding aptamers as proof-of-concept. In particular, the functionalization of a th...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707062/ https://www.ncbi.nlm.nih.gov/pubmed/36457701 http://dx.doi.org/10.1016/j.omtn.2022.11.007 |