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From mesenchymal niches to engineered in vitro model systems: Exploring and exploiting biomechanical regulation of vertebrate hedgehog signalling

Tissue patterning is the result of complex interactions between transcriptional programs and various mechanical cues that modulate cell behaviour and drive morphogenesis. Vertebrate Hedgehog signalling plays key roles in embryogenesis and adult tissue homeostasis, and is central to skeletal developm...

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Detalles Bibliográficos
Autores principales: Ghuloum, Fatmah I., Johnson, Colin A., Riobo-Del Galdo, Natalia A., Amer, Mahetab H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707069/
https://www.ncbi.nlm.nih.gov/pubmed/36457847
http://dx.doi.org/10.1016/j.mtbio.2022.100502