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Causal cascade of direct and indirect effects of anifrolumab on patient-reported outcomes: structural equation modelling of two Phase 3 trials

OBJECTIVES: SLE significantly impairs health-related quality of life (HRQoL). In this post hoc analysis, structural equation modelling was used to examine the ‘causal cascade’ of interaction between anifrolumab, disease activity and patient-reported outcomes (PROs) in pooled data from the phase 3 TU...

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Detalles Bibliográficos
Autores principales: Stull, Donald, O’Quinn, Sean, Williams, Betsy, Bean, Stephanie, Schwetje, Erik, Abreu, Gabriel, Tummala, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707104/
https://www.ncbi.nlm.nih.gov/pubmed/35274691
http://dx.doi.org/10.1093/rheumatology/keac138