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Blocking lncRNA-SNHG16 sensitizes gastric cancer cells to 5-Fu through targeting the miR-506-3p-PTBP1-mediated glucose metabolism

BACKGROUND: Gastric cancer (GC) is a commonly occurring human malignancy. The 5-fluorouracil (5-Fu) is a first-line anti-gastric cancer agent. However, a large number of GC patients developed 5-Fu resistance. Currently, the roles and molecular mechanisms of the lncRNA-SNHG16-modulated 5-Fu resistanc...

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Detalles Bibliográficos
Autores principales: Ding, Yan, Gao, Sujie, Zheng, Jiabin, Chen, Xuebo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707261/
https://www.ncbi.nlm.nih.gov/pubmed/36447254
http://dx.doi.org/10.1186/s40170-022-00293-w