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Autophagic degradation of CNS myelin maintains axon integrity

(Macro)autophagy is a major lysosome-dependent degradation mechanism which engulfs, removes and recycles unwanted cytoplasmic material, including damaged organelles and toxic protein aggregates. Although a few studies implicate autophagy in CNS demyelinating pathologies, its role, particularly in ma...

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Detalles Bibliográficos
Autores principales: Ktena, Niki, Kaplanis, Stefanos Ioannis, Kolotuev, Irina, Georgilis, Alexandros, Kallergi, Emmanouela, Stavroulaki, Vasiliki, Nikoletopoulou, Vassiliki, Savvaki, Maria, Karagogeos, Domna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707329/
https://www.ncbi.nlm.nih.gov/pubmed/36478958
http://dx.doi.org/10.15698/cst2022.12.274