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Ferulic acid alleviates alveolar epithelial barrier dysfunction in sepsis-induced acute lung injury by activating the Nrf2/HO-1 pathway and inhibiting ferroptosis

CONTEXT: Ferulic acid (FA) has antioxidative and anti-inflammatory effects, and is a promising drug to treat sepsis. OBJECTIVE: To study the therapeutic effect of FA in sepsis-induced acute lung injury (ALI) and its underlying mechanisms. MATERIALS AND METHODS: The caecal ligation and puncture (CLP)...

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Detalles Bibliográficos
Autores principales: Tang, Xianming, Liu, Jiqiang, Yao, Shuo, Zheng, Jianfei, Gong, Xun, Xiao, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707381/
https://www.ncbi.nlm.nih.gov/pubmed/36433644
http://dx.doi.org/10.1080/13880209.2022.2147549