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Recent progress on the activation of the cGAS–STING pathway and its regulation by biomolecular condensation

The cyclic guanosine monophosphate (GMP)–adenosine monophosphate (AMP) synthetase (cGAS)–stimulator of interferon genes (STING) pathway, comprising the DNA sensor cGAS, the second messenger cyclic GMP–AMP (cGAMP), and the endoplasmic reticulum (ER) adaptor protein STING, detects cytoplasmic double-s...

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Detalles Bibliográficos
Autores principales: Yu, Xiaoyu, Zhao, Zhen, Jiang, Zhengfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707564/
https://www.ncbi.nlm.nih.gov/pubmed/35803579
http://dx.doi.org/10.1093/jmcb/mjac042