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The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands
RIG-I is an essential innate immune receptor for detecting and responding to infection by RNA viruses. RIG-I specifically recognizes the unique molecular features of viral RNA molecules and selectively distinguishes them from closely-related RNAs abundant in host cells. The physical basis for this e...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707737/ https://www.ncbi.nlm.nih.gov/pubmed/36272408 http://dx.doi.org/10.1016/j.molcel.2022.09.029 |