Inducible degradation of the Drosophila Mediator subunit Med19 reveals its role in regulating developmental but not constitutively-expressed genes

The multi-subunit Mediator complex plays a critical role in gene expression by bridging enhancer-bound transcription factors and the RNA polymerase II machinery. Although experimental case studies suggest differential roles of Mediator subunits, a comprehensive view of the specific set of genes regu...

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Detalles Bibliográficos
Autores principales: Jullien, Denis, Guillou, Emmanuelle, Bernat-Fabre, Sandra, Payet, Adeline, Bourbon, Henri-Marc G., Boube, Muriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707739/
https://www.ncbi.nlm.nih.gov/pubmed/36445897
http://dx.doi.org/10.1371/journal.pone.0275613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707739/
https://www.ncbi.nlm.nih.gov/pubmed/36445897
http://dx.doi.org/10.1371/journal.pone.0275613

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