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Inducible degradation of the Drosophila Mediator subunit Med19 reveals its role in regulating developmental but not constitutively-expressed genes
The multi-subunit Mediator complex plays a critical role in gene expression by bridging enhancer-bound transcription factors and the RNA polymerase II machinery. Although experimental case studies suggest differential roles of Mediator subunits, a comprehensive view of the specific set of genes regu...
Autores principales: | Jullien, Denis, Guillou, Emmanuelle, Bernat-Fabre, Sandra, Payet, Adeline, Bourbon, Henri-Marc G., Boube, Muriel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707739/ https://www.ncbi.nlm.nih.gov/pubmed/36445897 http://dx.doi.org/10.1371/journal.pone.0275613 |
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