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Hsa_circ_0016070/micro‐340‐5p Axis Accelerates Pulmonary Arterial Hypertension Progression by Upregulating TWIST1 Transcription Via TCF4/β‐Catenin Complex

BACKGROUND: Hypoxia is considered a major leading cause of pulmonary hypertension (PH). In this study, the roles and molecular mechanism of circ_0016070 in PH were studied. METHODS AND RESULTS: The expression of circ_0016070 in serum samples, human pulmonary artery smooth muscle cells and hypoxia/mo...

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Detalles Bibliográficos
Autores principales: Huang, Chun‐Xia, Jiang, Zhi‐Xin, Du, Da‐Yong, Zhang, Zhi‐Min, Liu, Yang, Li, Yun‐Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707813/
https://www.ncbi.nlm.nih.gov/pubmed/35861841
http://dx.doi.org/10.1161/JAHA.121.024147