Mother cells control daughter cell proliferation in intestinal organoids to minimize proliferation fluctuations

During renewal of the intestine, cells are continuously generated by proliferation. Proliferation and differentiation must be tightly balanced, as any bias toward proliferation results in uncontrolled exponential growth. Yet, the inherently stochastic nature of cells raises the question how such flu...

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Detalles Bibliográficos
Autores principales: Huelsz-Prince, Guizela, Kok, Rutger Nico Ulbe, Goos, Yvonne, Bruens, Lotte, Zheng, Xuan, Ellenbroek, Saskia, Van Rheenen, Jacco, Tans, Sander, van Zon, Jeroen S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708068/
https://www.ncbi.nlm.nih.gov/pubmed/36445322
http://dx.doi.org/10.7554/eLife.80682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708068/
https://www.ncbi.nlm.nih.gov/pubmed/36445322
http://dx.doi.org/10.7554/eLife.80682

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