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Mother cells control daughter cell proliferation in intestinal organoids to minimize proliferation fluctuations
During renewal of the intestine, cells are continuously generated by proliferation. Proliferation and differentiation must be tightly balanced, as any bias toward proliferation results in uncontrolled exponential growth. Yet, the inherently stochastic nature of cells raises the question how such flu...
Autores principales: | Huelsz-Prince, Guizela, Kok, Rutger Nico Ulbe, Goos, Yvonne, Bruens, Lotte, Zheng, Xuan, Ellenbroek, Saskia, Van Rheenen, Jacco, Tans, Sander, van Zon, Jeroen S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708068/ https://www.ncbi.nlm.nih.gov/pubmed/36445322 http://dx.doi.org/10.7554/eLife.80682 |
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