Activation of Delta-Opioid Receptor Protects ARPE19 Cells against Oxygen-Glucose Deprivation/Reoxygenation-Induced Necroptosis and Apoptosis by Inhibiting the Release of TNF-α

PURPOSE: Retinal ischemia–reperfusion injury (RIRI) is the basis of the pathology that leads to many retinal diseases and induces necroptosis and apoptosis. Tumor necrosis factor-α (TNF-α) is critically involved in necroptosis and apoptosis. Delta-opioid receptor (DOR) activation inhibits TNF-α rele...

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Detalles Bibliográficos
Autores principales: Guo, Runjie, Chen, Ping, Fu, Tiantian, Zhang, Ren, Zhu, Yuan, Jin, Nange, Xu, Hong, Xia, Yong, Tian, Xuesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708366/
https://www.ncbi.nlm.nih.gov/pubmed/36457949
http://dx.doi.org/10.1155/2022/2285663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708366/
https://www.ncbi.nlm.nih.gov/pubmed/36457949
http://dx.doi.org/10.1155/2022/2285663

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