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Losartan attenuates upstream vasculopathy in a modified piglet model of pulmonary vein stenosis: contribution of the Hippo pathway

BACKGROUND: Diffuse pulmonary vein stenosis (PVS) is an intractable congenital heart disease for which the underlying mechanism remains unclear. In this study, we investigated the effect of losartan and the role of the Hippo pathway in PVS. METHODS: A total of 19 neonatal piglets were divided into 3...

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Detalles Bibliográficos
Autores principales: Zeng, Wenhui, Liu, Siming, Xu, Zhen, Ding, Fangbao, Mei, Ju, Zhu, Jiaquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708478/
https://www.ncbi.nlm.nih.gov/pubmed/36467357
http://dx.doi.org/10.21037/atm-22-2621