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Reprogramming of cancer-associated fibroblasts by apoptotic cancer cells inhibits lung metastasis via Notch1-WISP-1 signaling

The interplay between apoptotic cancer cells and the tumor microenvironment modulates cancer progression and metastasis. Cancer-associated fibroblasts (CAFs) play a crucial role in promoting these events through paracrine communication. Here, we demonstrate that conditioned medium (CM) from lung CAF...

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Detalles Bibliográficos
Autores principales: Kim, Hee Ja, Yang, Kyungwon, Kim, Kiyoon, Lee, Ye‐Ji, Lee, Sieun, Ahn, Sung Yong, Ahn, Young‐Ho, Kang, Jihee Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708692/
https://www.ncbi.nlm.nih.gov/pubmed/36241874
http://dx.doi.org/10.1038/s41423-022-00930-w