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p53 triggers mitochondrial apoptosis following DNA damage-dependent replication stress by the hepatotoxin methyleugenol

Liver cancer is one of the most frequent tumor entities worldwide, which is causally linked to viral infection, fatty liver disease, life-style factors and food-borne carcinogens, particularly aflatoxins. Moreover, genotoxic plant toxins including phenylpropenes are suspected human liver carcinogens...

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Detalles Bibliográficos
Autores principales: Carlsson, Max J., Vollmer, Anastasia S., Demuth, Philipp, Heylmann, Daniel, Reich, Diana, Quarz, Caroline, Rasenberger, Birgit, Nikolova, Teodora, Hofmann, Thomas G., Christmann, Markus, Fuhlbrueck, Julia A., Stegmüller, Simone, Richling, Elke, Cartus, Alexander T., Fahrer, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708695/
https://www.ncbi.nlm.nih.gov/pubmed/36446765
http://dx.doi.org/10.1038/s41419-022-05446-9