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p53 triggers mitochondrial apoptosis following DNA damage-dependent replication stress by the hepatotoxin methyleugenol
Liver cancer is one of the most frequent tumor entities worldwide, which is causally linked to viral infection, fatty liver disease, life-style factors and food-borne carcinogens, particularly aflatoxins. Moreover, genotoxic plant toxins including phenylpropenes are suspected human liver carcinogens...
Autores principales: | Carlsson, Max J., Vollmer, Anastasia S., Demuth, Philipp, Heylmann, Daniel, Reich, Diana, Quarz, Caroline, Rasenberger, Birgit, Nikolova, Teodora, Hofmann, Thomas G., Christmann, Markus, Fuhlbrueck, Julia A., Stegmüller, Simone, Richling, Elke, Cartus, Alexander T., Fahrer, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708695/ https://www.ncbi.nlm.nih.gov/pubmed/36446765 http://dx.doi.org/10.1038/s41419-022-05446-9 |
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