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MiR-148a deletion protects from bone loss in physiological and estrogen-deficient mice by targeting NRP1

Bone metabolic homeostasis is largely dependent on the dynamic balance between osteoblasts and osteoclasts. MicroRNAs (miRNAs) play critical roles in regulating bone metabolism. In this study, we explored the role of a new miRNA (miR-148a) in osteoporosis. We compared the bone phenotype between miR-...

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Detalles Bibliográficos
Autores principales: Pan, Bin, Zheng, Lin, Liu, Shijie, Fang, Jiawei, Lou, Chao, Hu, Xingyu, Ye, Lin, Lai, Hehuan, Gao, Jiawei, Zhang, Yejin, Ni, Kainan, He, Dengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708754/
https://www.ncbi.nlm.nih.gov/pubmed/36446758
http://dx.doi.org/10.1038/s41420-022-01261-5