PERIOD 2 regulates low-dose radioprotection via PER2/pGSK3β/β-catenin/Per2 loop

During evolution, humans are acclimatized to the stresses of natural radiation and circadian rhythmicity. Radiosensitivity of mammalian cells varies in the circadian period and adaptive radioprotection can be induced by pre-exposure to low-level radiation (LDR). It is unclear, however, if clock prot...

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Detalles Bibliográficos
Autores principales: Alexandrou, Aris T., Duan, Yixin, Xu, Shanxiu, Tepper, Clifford, Fan, Ming, Tang, Jason, Berg, Jonathan, Basheer, Wassim, Valicenti, Tyler, Wilson, Paul F., Coleman, Matthew A., Vaughan, Andrew T., Fu, Loning, Grdina, David J., Murley, Jefferey, Wang, Aijun, Woloschak, Gayle, Li, Jian Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708791/
https://www.ncbi.nlm.nih.gov/pubmed/36465103
http://dx.doi.org/10.1016/j.isci.2022.105546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708791/
https://www.ncbi.nlm.nih.gov/pubmed/36465103
http://dx.doi.org/10.1016/j.isci.2022.105546

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