Blockage of lamin-A/C loss diminishes the pro-inflammatory macrophage response

Mutations and defects in nuclear lamins can cause major pathologies, including inflammation and inflammatory diseases. Yet, the underlying molecular mechanisms are not known. We now report that the pro-inflammatory activation of macrophages, as induced by LPS or pathogenic E. coli, reduces Lamin-A/C...

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Detalles Bibliográficos
Autores principales: Mehl, Johanna L., Earle, Ashley, Lammerding, Jan, Mhlanga, Musa, Vogel, Viola, Jain, Nikhil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708799/
https://www.ncbi.nlm.nih.gov/pubmed/36465100
http://dx.doi.org/10.1016/j.isci.2022.105528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708799/
https://www.ncbi.nlm.nih.gov/pubmed/36465100
http://dx.doi.org/10.1016/j.isci.2022.105528

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