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Beta-3 adrenergic receptor overexpression reverses aortic stenosis–induced heart failure and restores balanced mitochondrial dynamics

Aortic stenosis (AS) is associated with left ventricular (LV) hypertrophy and heart failure (HF). There is a lack of therapies able to prevent/revert AS-induced HF. Beta3 adrenergic receptor (β3AR) signaling is beneficial in several forms of HF. Here, we studied the potential beneficial effect of β3...

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Detalles Bibliográficos
Autores principales: Pun-García, Andrés, Clemente-Moragón, Agustín, Villena-Gutierrez, Rocio, Gómez, Monica, Sanz-Rosa, David, Díaz-Guerra, Anabel, Prados, Belén, Medina, Juan Pablo, Montó, Fermí, Ivorra, Maria Dolores, Márquez-López, Cristina, Cannavo, Alessandro, Bernal, Juan A., Koch, Walter J., Fuster, Valentin, de la Pompa, José Luis, Oliver, Eduardo, Ibanez, Borja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708808/
https://www.ncbi.nlm.nih.gov/pubmed/36445563
http://dx.doi.org/10.1007/s00395-022-00966-z