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Beta-3 adrenergic receptor overexpression reverses aortic stenosis–induced heart failure and restores balanced mitochondrial dynamics
Aortic stenosis (AS) is associated with left ventricular (LV) hypertrophy and heart failure (HF). There is a lack of therapies able to prevent/revert AS-induced HF. Beta3 adrenergic receptor (β3AR) signaling is beneficial in several forms of HF. Here, we studied the potential beneficial effect of β3...
Autores principales: | Pun-García, Andrés, Clemente-Moragón, Agustín, Villena-Gutierrez, Rocio, Gómez, Monica, Sanz-Rosa, David, Díaz-Guerra, Anabel, Prados, Belén, Medina, Juan Pablo, Montó, Fermí, Ivorra, Maria Dolores, Márquez-López, Cristina, Cannavo, Alessandro, Bernal, Juan A., Koch, Walter J., Fuster, Valentin, de la Pompa, José Luis, Oliver, Eduardo, Ibanez, Borja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708808/ https://www.ncbi.nlm.nih.gov/pubmed/36445563 http://dx.doi.org/10.1007/s00395-022-00966-z |
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