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Ion selectivity mechanism of the MgtE channel for Mg(2+) over Ca(2+)

MgtE is a Mg(2+)-selective ion channel whose orthologs are widely distributed from prokaryotes to eukaryotes, including humans, and are important participants in the maintenance of cellular Mg(2+) homeostasis. The previous high-resolution structure determination of the MgtE transmembrane (TM) domain...

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Detalles Bibliográficos
Autores principales: Teng, Xinyu, Sheng, Danqi, Wang, Jin, Yu, Ye, Hattori, Motoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708914/
https://www.ncbi.nlm.nih.gov/pubmed/36465111
http://dx.doi.org/10.1016/j.isci.2022.105565