Hepatocyte-derived GDF15 suppresses feeding and improves insulin sensitivity in obese mice

Growth differentiation factor 15 (GDF15) is a stress-induced secreted protein whose circulating levels are increased in the context of obesity. Recombinant GDF15 reduces body weight and improves glycemia in obese models, which is largely attributed to the central action of GDF15 to suppress feeding...

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Detalles Bibliográficos
Autores principales: Xie, Bingxian, Murali, Anjana, Vandevender, Amber M., Chen, Jeffrey, Silva, Agustin Gil, Bello, Fiona M., Chuan, Byron, Bahudhanapati, Harinath, Sipula, Ian, Dedousis, Nikolaos, Shah, Faraaz A., O’Donnell, Christopher P., Alder, Jonathan K., Jurczak, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708916/
https://www.ncbi.nlm.nih.gov/pubmed/36465107
http://dx.doi.org/10.1016/j.isci.2022.105569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708916/
https://www.ncbi.nlm.nih.gov/pubmed/36465107
http://dx.doi.org/10.1016/j.isci.2022.105569

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