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The Mechano-Ubiquitinome of Articular Cartilage: Differential Ubiquitination and Activation of a Group of ER-Associated DUBs and ER Stress Regulators

Understanding how connective tissue cells respond to mechanical stimulation is important to human health and disease processes in musculoskeletal diseases. Injury to articular cartilage is a key risk factor in predisposition to tissue damage and degenerative osteoarthritis. Recently, we have discove...

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Detalles Bibliográficos
Autores principales: Kaokhum, Nitchakarn, Pinto-Fernández, Adán, Wilkinson, Mark, Kessler, Benedikt M., Ismail, Heba M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708921/
https://www.ncbi.nlm.nih.gov/pubmed/36182100
http://dx.doi.org/10.1016/j.mcpro.2022.100419