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Estimation of the Minimal Rift Valley Fever Virus Protective Neutralizing Antibody Titer in Human Volunteers Immunized with MP-12 Vaccine Based on Protection in a Mouse Model of Disease

The Rift Valley fever virus (RVFV) MP-12 vaccine is a promising human and veterinary vaccine. Although the vaccine elicited neutralizing antibody (nAb) in human volunteers, the minimal antibody titer that is needed to afford protection is unknown. Therefore, this study was conducted to determine the...

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Detalles Bibliográficos
Autores principales: Watts, Douglas M., Westover, Jonna L.B., Palermo, Pedro M., Bailey, Kevin W., Morrill, John C., Bettinger, George E., Monath, Thomas P., Smith, Darci R., Peters, Clarence J., Pittman, Phillip R., Orbegozo, Jeanette, Gowen, Brian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709016/
https://www.ncbi.nlm.nih.gov/pubmed/36122681
http://dx.doi.org/10.4269/ajtmh.22-0356