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Estimation of the Minimal Rift Valley Fever Virus Protective Neutralizing Antibody Titer in Human Volunteers Immunized with MP-12 Vaccine Based on Protection in a Mouse Model of Disease
The Rift Valley fever virus (RVFV) MP-12 vaccine is a promising human and veterinary vaccine. Although the vaccine elicited neutralizing antibody (nAb) in human volunteers, the minimal antibody titer that is needed to afford protection is unknown. Therefore, this study was conducted to determine the...
Autores principales: | Watts, Douglas M., Westover, Jonna L.B., Palermo, Pedro M., Bailey, Kevin W., Morrill, John C., Bettinger, George E., Monath, Thomas P., Smith, Darci R., Peters, Clarence J., Pittman, Phillip R., Orbegozo, Jeanette, Gowen, Brian B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Tropical Medicine and Hygiene
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709016/ https://www.ncbi.nlm.nih.gov/pubmed/36122681 http://dx.doi.org/10.4269/ajtmh.22-0356 |
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