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m(6)A-modified circFNDC3B inhibits colorectal cancer stemness and metastasis via RNF41-dependent ASB6 degradation

Colorectal cancer (CRC) is the third most frequently diagnosed cancer with unfavorable clinical outcomes worldwide. circFNDC3B plays as a tumor suppressor in CRC, however, the mechanism of circFNDC3B in CRC remains ambiguous. The stem-like properties of CRC cells were detected by the evaluation of s...

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Detalles Bibliográficos
Autores principales: Zeng, Wei, Zhu, Jin-Feng, Guo, Jian, Huang, Gen-Jie, Ai, Li-Sha, Zeng, Yu, Liao, Wang-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709059/
https://www.ncbi.nlm.nih.gov/pubmed/36446779
http://dx.doi.org/10.1038/s41419-022-05451-y