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A meta-analysis of pre-pregnancy maternal body mass index and placental DNA methylation identifies 27 CpG sites with implications for mother-child health

Higher maternal pre-pregnancy body mass index (ppBMI) is associated with increased neonatal morbidity, as well as with pregnancy complications and metabolic outcomes in offspring later in life. The placenta is a key organ in fetal development and has been proposed to act as a mediator between the mo...

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Detalles Bibliográficos
Autores principales: Fernandez-Jimenez, Nora, Fore, Ruby, Cilleros-Portet, Ariadna, Lepeule, Johanna, Perron, Patrice, Kvist, Tuomas, Tian, Fu-Ying, Lesseur, Corina, Binder, Alexandra M., Lozano, Manuel, Martorell-Marugán, Jordi, Loke, Yuk J., Bakulski, Kelly M., Zhu, Yihui, Forhan, Anne, Sammallahti, Sara, Everson, Todd M., Chen, Jia, Michels, Karin B., Belmonte, Thalia, Carmona-Sáez, Pedro, Halliday, Jane, Daniele Fallin, M., LaSalle, Janine M., Tost, Jorg, Czamara, Darina, Fernández, Mariana F., Gómez-Martín, Antonio, Craig, Jeffrey M., Gonzalez-Alzaga, Beatriz, Schmidt, Rebecca J., Dou, John F., Muggli, Evelyne, Lacasaña, Marina, Vrijheid, Martine, Marsit, Carmen J., Karagas, Margaret R., Räikkönen, Katri, Bouchard, Luigi, Heude, Barbara, Santa-Marina, Loreto, Bustamante, Mariona, Hivert, Marie-France, Bilbao, Jose Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709064/
https://www.ncbi.nlm.nih.gov/pubmed/36446949
http://dx.doi.org/10.1038/s42003-022-04267-y