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Spatiotemporal control of necroptotic cell death and plasma membrane recruitment using engineered MLKL domains
Necroptosis is a form of programmed necrotic cell death in which a signaling cascade induces oligomerization of mixed lineage kinase domain-like (MLKL) protein, leading to plasma membrane rupture. Necroptotic cell death is recognized as important for protection against viral infection and has roles...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709077/ https://www.ncbi.nlm.nih.gov/pubmed/36446770 http://dx.doi.org/10.1038/s41420-022-01258-0 |